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Environmental protection --- Decision making. --- United States. --- U.S. Environmental Protection Agency --- US Environmental Protection Agency --- EPA --- Agentstvo po okhrane okruzhai︠u︡shcheĭ sredy SShA --- E.P.A. --- USEPA --- United States Environmental Protection Agency --- US EPA --- Environmental Protection Agency (U.S.)

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614.7 --- Hygiene of air, water, soil. Pollution and its control --- Pollutie van lucht, water, grond--(openbare gezondheidszorg) --- Environmental policy --- United States --- United States. Environmental Protection Agency --- United States. --- U.S. Environmental Protection Agency --- US Environmental Protection Agency --- EPA --- Agentstvo po okhrane okruzhai︠u︡shcheĭ sredy SShA --- E.P.A. --- USEPA --- United States Environmental Protection Agency --- US EPA --- Environmental Protection Agency (U.S.)

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"The U.S. Environmental Protection Agency (EPA) has a mission and regulatory responsibility to protect human health and the environment. EPA's pursuit of that goal includes a variety of research activities involving human subjects, such as epidemiologic studies and surveys. Those research activities also involve studies of individuals who volunteer to be exposed to air pollutants intentionally in controlled laboratory settings so that measurements can be made of transient and reversible biomarker or physiologic responses to those exposures that can indicate pathways of toxicity and mechanisms of air-pollution responses. The results of those controlled human inhalation exposure (CHIE) studies, also referred to as human clinical studies or human challenge studies, are used to inform policy decisions and help establish or revise standards to protect public health and improve air quality. Controlled Human Inhalation-Exposure Studies at EPA addresses scientific issues and provides guidance on the conduct of CHIE studies. This report assesses the utility of CHIE studies to inform and reduce uncertainties in setting air-pollution standards to protect public health and assess whether continuation of such studies is warranted. It also evaluates the potential health risks to test subjects who participated in recent studies of air pollutants at EPA's clinical research facility"--

Pollutants --- Health aspects. --- United States. --- Chemical pollutants --- Contaminants, Environmental --- Environmental contaminants --- Environmental pollutants --- Chemicals --- Pollution --- Agentstvo po okhrane okruzhai͡ushcheĭ sredy SShA --- E.P.A. --- Environmental Protection Agency (U.S.) --- EPA --- U.S. Environmental Protection Agency --- United States Environmental Protection Agency --- US Environmental Protection Agency --- US EPA --- USEPA --- Agentstvo po okhrane okruzhai︠u︡shcheĭ sredy SShA

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Dioxins --- Tetrachlorodibenzodioxin --- Heterocyclic compounds --- Hazardous substances --- Toxicology. --- Carcinogenicity. --- Derivatives --- United States. --- U.S. Environmental Protection Agency --- US Environmental Protection Agency --- EPA --- Agentstvo po okhrane okruzhai︠u︡shcheĭ sredy SShA --- E.P.A. --- USEPA --- United States Environmental Protection Agency --- US EPA --- Environmental Protection Agency (U.S.)

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Drinking water --- Drinking water standards --- Water --- Water-supply --- Contamination of drinking water --- Contamination. --- Standards. --- Composition --- Pollution --- United States. --- Agentstvo po okhrane okruzhai͡ushcheĭ sredy SShA --- E.P.A. --- Environmental Protection Agency (U.S.) --- EPA --- U.S. Environmental Protection Agency --- United States Environmental Protection Agency --- US Environmental Protection Agency --- US EPA --- USEPA --- Agentstvo po okhrane okruzhai︠u︡shcheĭ sredy SShA